CAH (Congenital Adrenal Hyperplasia) is a group of related genetic variations that affect the enzymes allowing the adrenal glands to produce specific hormones regulating body functions. People with CAH do not consistently produce the required amounts of cortisol (stress/sickness response), aldosterone (potassium/sodium regulation), or both, and may naturally produce higher-than-typical levels of androgens like testosterone to compensate.
Salt-Wasting CAH is a subtype of classic CAH that causes “salt-wasting,” a dangerous condition where low aldosterone levels lead to excessive sodium loss. People with this form can experience life-threatening adrenal crises, especially when stressed (e.g., due to illness, infection, or surgery).
